House M.D. Trivia
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187 free House M.D. trivia questions with answers — entertainment quiz, new questions added Oct 2026.
40 free House M.D. trivia questions with answers. House M.D. was the most-watched TV show on Earth in 2008, and this quiz treats it accordingly. Forty questions cover Dr. Gregory House and his team at Princeton-Plainsboro, the Sherlock Holmes homages hidden in plain sight, the Vicodin, the cane, the whiteboard, the guest villains, the bus crash, the psychiatric hospital, the prison, and the finale that sent House and Wilson off on motorcycles. It starts with House MD trivia any fan can answer and works up to the production stories: the audition tape shot in a hotel bathroom, the director who thought Hugh Laurie was American, and why Kutner had to die. Difficulty ratings are shown so you can pick your battles. Every answer was checked against Wikipedia's articles on the series, its characters and episodes, and each question carries its source.
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Q 01On which network did House air from 2004 to 2012?
Fox
House aired on Fox for eight seasons and 177 episodes, from November 16, 2004 to May 21, 2012.
Q 02Who created House?
David Shore
David Shore created House and served as its showrunner for all eight seasons; he gave the misanthropic hero his voice and directed the series finale himself.
Q 03Which motor event does House love enough to take Cameron along in season one?
A monster truck rally
A monster truck rally: House has two all-access tickets, and when Wilson cannot make it he takes Cameron instead.
Q 04What is House's medical double specialty?
Infectious disease and nephrology
Infectious disease and nephrology are his board certifications, and tenure is his shield: in the pilot he tells Cuddy she cannot fire him.
Q 05Which painkiller is House dependent on?
Vicodin
The season eight premiere is titled Twenty Vicodin, after the stash he needs to get through his last days in prison.
Q 06What caused the damage to House's right leg?
An infarction in his thigh muscle
An infarction in his thigh muscle: an aneurysm clotted during a golf game, was misdiagnosed for days, and Stacy authorised removing the dead muscle while he was in a coma.
Q 07What is the street address of House's apartment?
221B Baker
221B Baker Street is Sherlock Holmes's London address, borrowed on purpose: House is a Holmes for medicine, with Wilson as his Watson.
Q 08Under what name is the gunman who shoots House in the season two finale credited?
Moriarty
Moriarty, the name of Holmes's nemesis, is how the credits list the shooter in No Reason, and most of what follows turns out to be House's hallucination.
Q 09Which hospital department does House's only real friend, Dr. James Wilson, head?
Oncology
Oncology head Wilson writes most of House's painkiller prescriptions, so in season three a detective freezes his bank account and suspends his prescribing.
Q 10In House, what is Dr. Lisa Cuddy's job at the hospital?
Dean of Medicine
Dean of Medicine and chief administrator; Lisa Edelstein left the show after season seven when a salary cut was proposed.
Q 11What is Dr. Eric Foreman's medical specialty?
Neurology
Neurology is Foreman's field; in season two he catches a patient's deadly brain infection and, believing he is dying, asks Cameron to be his medical proxy.
Q 12Which actress plays immunologist Dr. Allison Cameron?
Jennifer Morrison
Jennifer Morrison's Cameron walks out of her marriage and the hospital in season six after learning Chase let a dictator die; the actress returned for the finale.
Q 13Which genetic condition does Thirteen inherit from her mother?
Huntington's
Huntington's killed her mother; Thirteen tests positive at the end of season four and, after a self-destructive spell, joins a drug trial for the disease.
Q 21House's most-watched episode, Frozen, drew about 29 million viewers by airing straight after which event?
The Super Bowl
The Super Bowl: Frozen followed Super Bowl XLII in February 2008, with Mira Sorvino as a psychiatrist stranded at the South Pole whom House has to diagnose by video link.
Q 22Which billionaire, played by Chi McBride, tries to fire House in season one?
Edward Vogler
Edward Vogler, a pharmaceutical mogul, buys the chairmanship of the hospital board and demands House's dismissal, but the board votes to keep House and lose the money.
Q 23Why does Detective Michael Tritter, played by David Morse, pursue House in season three?
He was left with a rectal thermometer
Q 14Kutner was written out in season five because actor Kal Penn took a job where?
The White House
The White House: Penn joined Barack Obama's Office of Public Engagement, so the writers gave Kutner a sudden death that the team never manages to explain.
Q 15Which member of the later team is a former plastic surgeon?
Taub
Taub gave up a lucrative plastic surgery practice after an affair with a nurse there, which his partners agreed to keep from his wife if he left.
Q 16How did House recruit his new team in season four?
Through a reality-show style elimination contest
Through a reality-show style elimination contest: House gives the applicants numbers instead of learning their names, then fires them a few at a time over the season.
Q 17Which Massive Attack song is House's opening theme in the United States?
Teardrop
Teardrop, from Massive Attack's 1998 album Mezzanine, opens US episodes; many broadcasts outside the US swapped in an instrumental written for the show.
Q 18Where did Hugh Laurie record his audition tape for House?
A hotel bathroom in Namibia
A hotel bathroom in Namibia was the only place with enough light, Laurie said; he was there filming Flight of the Phoenix when the role came up.
Q 19Which director of the pilot did not realise Hugh Laurie was English?
Bryan Singer
Bryan Singer held up the audition tape as proof that he wanted an American for the part; Laurie puts his accent down to a misspent youth in front of the screen.
Q 20In which year was House the most-watched television programme in the world?
2008
Eurodata TV Worldwide, which tracks ratings across dozens of countries, named House the most-watched television programme in the world for 2008.
He was left with a rectal thermometer in an exam room after tripping House; refused an apology, he digs into House's pill habit and takes him to court.
Q 24Which actress plays Stacy Warner, House's ex-girlfriend, in seasons one and two?
Sela Ward
Sela Ward played Stacy Warner, a lawyer who authorised the leg surgery that ended their relationship and returns in season two as the hospital's counsel.
Q 25How does Amber Volakis, Wilson's girlfriend, die in House's season four finale?
A bus crash
A bus crash: House, a fellow passenger left with amnesia, pieces together that Amber was aboard, and her damaged kidneys cannot clear the amantadine she had taken.
Q 26Where does House spend the two-hour season six premiere, Broken?
A psychiatric hospital
He checks into Mayfield, a psychiatric hospital, to come off Vicodin after hallucinating Amber through the end of season five.
Q 27What does House do to Cuddy's home in the season seven finale of House?
Drives his car into her house
Drives his car into her house: he rams the dining room after Cuddy ends their relationship over his addiction, and starts season eight in prison.
Q 28Which team member takes over as head of the hospital in the final season?
Foreman
Chase ends the series running the Department of Diagnostic Medicine that House left behind.
Q 29What is the title of House's series finale?
Everybody Dies
Everybody Dies, directed by David Shore, bookends the pilot's alternate title, Everybody Lies; the retrospective Swan Song aired just before it on May 21, 2012.
Q 30How does House escape his troubles in the series finale?
He fakes his death in a fire
He fakes his death in a fire by switching his dental records for a dead patient's, giving up medicine for good rather than go back to jail while Wilson is dying.